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Target
Orotidine 5'-phosphate decarboxylase
Ligand
BDBM50231945
Substrate
n/a
Meas. Tech.
ChEMBL_460800 (CHEMBL944741)
Ki
400±n/a nM
Citation
 Poduch, E; Wei, L; Pai, EF; Kotra, LP Structural diversity and plasticity associated with nucleotides targeting orotidine monophosphate decarboxylase. J Med Chem 51:432-8 (2008) [PubMed]  Article 
Target
Name:
Orotidine 5'-phosphate decarboxylase
Synonyms:
Orotidine phosphate decarboxylase | PYRF_YEAST | URA3
Type:
PROTEIN
Mol. Mass.:
29241.18
Organism:
Saccharomyces cerevisiae
Description:
ChEMBL_639015
Residue:
267
Sequence:
MSKATYKERAATHPSPVAAKLFNIMHEKQTNLCASLDVRTTKELLELVEALGPKICLLKTHVDILTDFSMEGTVKPLKALSAKYNFLLFEDRKFADIGNTVKLQYSAGVYRIAEWADITNAHGVVGPGIVSGLKQAAEEVTKEPRGLLMLAELSCKGSLATGEYTKGTVDIAKSDKDFVIGFIAQRDMGGRDEGYDWLIMTPGVGLDDKGDALGQQYRTVDDVVSTGSDIIIVGRGLFAKGRDAKVEGERYRKAGWEAYLRRCGQQN
  
Inhibitor
Name:
BDBM50231945
Synonyms:
CHEMBL253328 | xanthosine-5'-monophosphate disodium salt
Type:
Small organic molecule
Emp. Form.:
C10H11N4O9P
Mol. Mass.:
362.1906
SMILES:
O[C@@H]1[C@@H](COP([O-])([O-])=O)O[C@H]([C@@H]1O)n1cnc2c1[nH]c(=O)[nH]c2=O
Structure:
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