Reaction Details Report a problem with these data
Target
C-X-C chemokine receptor type 3
Ligand
BDBM50375120
Substrate
n/a
Meas. Tech.
ChEMBL_470260 (CHEMBL950215)
IC50
40±n/a nM
Citation
 Hayes, ME; Breinlinger, EC; Wallace, GA; Grongsaard, P; Miao, W; McPherson, MJ; Stoffel, RH; Green, DW; Roth, GP Lead identification of 2-iminobenzimidazole antagonists of the chemokine receptor CXCR3. Bioorg Med Chem Lett 18:2414-9 (2008) [PubMed]  Article 
Target
Name:
C-X-C chemokine receptor type 3
Synonyms:
CXCR3_MOUSE | Cmkar3 | Cxcr3
Type:
PROTEIN
Mol. Mass.:
41020.84
Organism:
Mus musculus
Description:
ChEMBL_560734
Residue:
367
Sequence:
MYLEVSERQVLDASDFAFLLENSTSPYDYGENESDFSDSPPCPQDFSLNFDRTFLPALYSLLFLLGLLGNGAVAAVLLSQRTALSSTDTFLLHLAVADVLLVLTLPLWAVDAAVQWVFGPGLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPRVRVALTCIVVWGLCLLFALPDFIYLSANYDQRLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILAVLLVSRGQRRFRAMRLVVVVVAAFAVCWTPYHLVVLVDILMDVGVLARNCGRESHVDVAKSVTSGMGYMHCCLNPLLYAFVGVKFREQMWMLFTRLGRSDQRGPQRQPSSSRRESSWSETTEASYLGL
  
Inhibitor
Name:
BDBM50375120
Synonyms:
CHEMBL403040
Type:
Small organic molecule
Emp. Form.:
C31H27Cl2N5O2
Mol. Mass.:
572.484
SMILES:
Clc1ccc(cc1)C(=O)Cn1c2cccc(Cl)c2n(CC[C@@H]2CCCN2C(=O)c2cccc3cccnc23)c1=N
Structure:
Search PDB for entries with ligand similarity: