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Target
Somatostatin receptor type 1
Ligand
BDBM50261397
Substrate
n/a
Meas. Tech.
ChEMBL_532742 (CHEMBL972316)
IC50
416±n/a nM
Citation
 Erchegyi, J; Grace, CR; Samant, M; Cescato, R; Piccand, V; Riek, R; Reubi, JC; Rivier, JE Ring size of somatostatin analogues (ODT-8) modulates receptor selectivity and binding affinity. J Med Chem 51:2668-75 (2008) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 1
Synonyms:
SOMATOSTATIN SST1 | SRIF-2 | SS-1-R | SS1-R | SS1R | SSR1_HUMAN | SSTR1 | Somatostatin receptor type 1 (SSTR1)
Type:
Enzyme
Mol. Mass.:
42692.81
Organism:
Homo sapiens (Human)
Description:
P30872
Residue:
391
Sequence:
MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL
  
Inhibitor
Name:
BDBM50261397
Synonyms:
(4R,7S,10S,13S,16R,19S,22S,25S)-25-Acetylamino-13-(4-amino-butyl)-7,19,22-tribenzyl-10-((R)-1-hydroxy-ethyl)-16-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24-heptaoxo-1,2-dithia-5,8,11,14,17,20,23-heptaaza-cyclopentacosane-4-carboxylic acid | CHEMBL525030
Type:
Small organic molecule
Emp. Form.:
C55H66N10O11S2
Mol. Mass.:
1107.303
SMILES:
C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(C)=O)SSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O |r|
Structure:
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