Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50317253
Substrate
n/a
Meas. Tech.
ChEMBL_631541 (CHEMBL1103906)
Ki
1811±n/a nM
Citation
 Lange, JH; van der Neut, MA; Borst, AJ; Yildirim, M; van Stuivenberg, HH; van Vliet, BJ; Kruse, CG Probing the cannabinoid CB1/CB2 receptor subtype selectivity limits of 1,2-diarylimidazole-4-carboxamides by fine-tuning their 5-substitution pattern. Bioorg Med Chem Lett 20:2770-5 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50317253
Synonyms:
1-(4-chlorophenyl)-2-(2,4-dichlorophenyl)-5-iodo-N-(piperidin-1-yl)-1H-imidazole-4-carboxamide | CHEMBL1088220
Type:
Small organic molecule
Emp. Form.:
C21H18Cl3IN4O
Mol. Mass.:
575.657
SMILES:
Clc1ccc(cc1)-n1c(I)c(nc1-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Structure:
Search PDB for entries with ligand similarity: