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Target
Cannabinoid receptor 2
Ligand
BDBM50324653
Substrate
n/a
Meas. Tech.
ChEMBL_649740 (CHEMBL1219438)
Ki
8±n/a nM
Citation
 Pasquini, S; Ligresti, A; Mugnaini, C; Semeraro, T; Cicione, L; De Rosa, M; Guida, F; Luongo, L; De Chiaro, M; Cascio, MG; Bolognini, D; Marini, P; Pertwee, R; Maione, S; Di Marzo, V; Corelli, F Investigations on the 4-quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands. J Med Chem 53:5915-28 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50324653
Synonyms:
CHEMBL1215963 | N-(Adamantan-1-yl)-6-(1H-imidazol-1-yl)-4-oxo-1-pentyl-1,4-dihydroquinoline-3-carboxamide
Type:
Small organic molecule
Emp. Form.:
C28H34N4O2
Mol. Mass.:
458.5952
SMILES:
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(ccc12)-n1ccnc1 |TLB:14:15:19:13.12.18,THB:14:13:19:15.20.16,16:17:12:15.20.14,16:15:12:17.19.18|
Structure:
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