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Target
Galectin-3
Ligand
BDBM50326587
Substrate
n/a
Meas. Tech.
ChEMBL_661835 (CHEMBL1252151)
Kd
520000±n/a nM
Citation
 Salameh, BA; Cumpstey, I; Sundin, A; Leffler, H; Nilsson, UJ 1H-1,2,3-triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors. Bioorg Med Chem 18:5367-78 (2010) [PubMed]  Article 
Target
Name:
Galectin-3
Synonyms:
LEG3_HUMAN | LGALS3 | MAC2
Type:
Enzyme
Mol. Mass.:
26156.54
Organism:
Homo sapiens (Human)
Description:
P17931
Residue:
250
Sequence:
MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
  
Inhibitor
Name:
BDBM50326587
Synonyms:
CHEMBL1255018 | Methyl-3-(4-(N'-morpholino)ethylaminocarbonyl)-1H-[1,2,3]-triazol-1-yl)-3-deoxy-1-thio-beta-D-galactopyranoside
Type:
Small organic molecule
Emp. Form.:
C16H27N5O6S
Mol. Mass.:
417.48
SMILES:
CS[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1O)n1cc(nn1)C(=O)NCCN1CCOCC1 |r|
Structure:
Search PDB for entries with ligand similarity: