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Target
MBT domain-containing protein 1
Ligand
BDBM50165019
Substrate
n/a
Meas. Tech.
ChEMBL_684951 (CHEMBL1286366)
IC50
>100000±n/a nM
Citation
 Kireev, D; Wigle, TJ; Norris-Drouin, J; Herold, JM; Janzen, WP; Frye, SV Identification of non-peptide malignant brain tumor (MBT) repeat antagonists by virtual screening of commercially available compounds. J Med Chem 53:7625-31 (2010) [PubMed]  Article 
Target
Name:
MBT domain-containing protein 1
Synonyms:
MBT domain-containing protein 1 | MBT domain-containing protein 1 (MBTD1) | MBTD1 | MBTD1_HUMAN
Type:
Protein
Mol. Mass.:
70557.67
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
628
Sequence:
MFDGYDSCSEDTSSSSSSEESEEEVAPLPSNLPIIKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLQKQPLVAKLAAYAQYQATLQNQAKTKAAVSMEGFSWGNYINSNSFIAAPVTCFKHAPMGTCWGDISENVRVEVPNTDCSLPTKVFWIAGIVKLAGYNALLRYEGFENDSGLDFWCNICGSDIHPVGWCAASGKPLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFKPCMRVEVVDKRHLCRTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWSRSIGHRFKRSDITKKQDGHFDTPPHLFAKVKEVDQSGEWFKEGMKLEAIDPLNLSTICVATIRKVLADGFLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETGSIAAPVKLFNKDVPNHGFRVGMKLEAVDLMEPRLICVATVTRIIHRLLRIHFDGWEEEYDQWVDCESPDLYPVGWCQLTGYQLQPPASQSSRENQSASSKQKKKAKSQQYKGHKKMTTLQLKEELLDGEDYNFLQGASDQESNGSANFYIKQEP
  
Inhibitor
Name:
BDBM50165019
Synonyms:
4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester | 4-(diethylamino)but-2-yn-1-yl cyclohexyl(hydroxy)phenylacetate | 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat | 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate | Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy-, 4-(diethylamino)-2-butynyl ester | CHEMBL1231 | Cyclohexaneglycolic acid, alpha-phenyl-, 4-(diethylamino)-2-butynyl ester | OXYBUTYNIN CHLORIDE
Type:
Small organic molecule
Emp. Form.:
C22H31NO3
Mol. Mass.:
357.4864
SMILES:
CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)c1ccccc1
Structure:
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