Reaction Details Report a problem with these data
Target
Lethal(3)malignant brain tumor-like protein 4
Ligand
BDBM50330504
Substrate
n/a
Meas. Tech.
ChEMBL_684950 (CHEMBL1286365)
IC50
>100000±n/a nM
Citation
 Kireev, D; Wigle, TJ; Norris-Drouin, J; Herold, JM; Janzen, WP; Frye, SV Identification of non-peptide malignant brain tumor (MBT) repeat antagonists by virtual screening of commercially available compounds. J Med Chem 53:7625-31 (2010) [PubMed]  Article 
Target
Name:
Lethal(3)malignant brain tumor-like protein 4
Synonyms:
H-l(3)mbt-like protein 4 | L(3)mbt-like protein 4 | L3MBTL4 | LMBL4_HUMAN
Type:
PROTEIN
Mol. Mass.:
71132.81
Organism:
Homo sapiens (Human)
Description:
ChEMBL_983407
Residue:
623
Sequence:
MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKEQKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDGYLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFRNRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVNSPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNMKLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHPLEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDRLREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLFRVLVLHPRGLEYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNSILMFRHSQELPEEDIASGQEVRG
  
Inhibitor
Name:
BDBM50330504
Synonyms:
3-(11H-dibenzo[b,f][1,4]oxathiepin-11-yl)-N-methylpropan-1-amine | CHEMBL1275667
Type:
Small organic molecule
Emp. Form.:
C17H19NOS
Mol. Mass.:
285.404
SMILES:
CNCCCC1Sc2ccccc2Oc2ccccc12
Structure:
Search PDB for entries with ligand similarity: