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Target
Prostaglandin D2 receptor
Ligand
BDBM50378988
Substrate
n/a
Meas. Tech.
ChEMBL_809592 (CHEMBL2015718)
IC50
>10000±n/a nM
Citation
 Liu, JJ; Cheng, AC; Tang, HL; Medina, JC Benzodiazepinone Derivatives as CRTH2 Antagonists. ACS Med Chem Lett 2:515-518 (2011) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor
Type:
Enzyme
Mol. Mass.:
40288.87
Organism:
Homo sapiens (Human)
Description:
Q13258
Residue:
359
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
  
Inhibitor
Name:
BDBM50378988
Synonyms:
CHEMBL2011452
Type:
Small organic molecule
Emp. Form.:
C25H21ClN2O4
Mol. Mass.:
448.898
SMILES:
COc1ccc(CC(O)=O)cc1C1=NCC(=O)N(Cc2cccc(Cl)c2)c2ccccc12 |t:13|
Structure:
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