Reaction Details Report a problem with these data
Target
Vasopressin V1a receptor
Ligand
BDBM50380760
Substrate
n/a
Meas. Tech.
ChEMBL_813469 (CHEMBL2019477)
Ki
78±n/a nM
Citation
 Smith, AL; Freeman, SM; Stehouwer, JS; Inoue, K; Voll, RJ; Young, LJ; Goodman, MM Synthesis and evaluation of C-11, F-18 and I-125 small molecule radioligands for detecting oxytocin receptors. Bioorg Med Chem 20:2721-38 (2012) [PubMed]  Article 
Target
Name:
Vasopressin V1a receptor
Synonyms:
AVPR V1a | Antidiuretic hormone receptor 1a | Avpr1a | V1AR_MICOH | V1aR | Vascular/hepatic-type arginine vasopressin receptor
Type:
PROTEIN
Mol. Mass.:
47578.66
Organism:
Microtus ochrogaster
Description:
ChEMBL_813469
Residue:
420
Sequence:
MSFPRGSYDPAASNSSPWWPLSAEDANSSWEAAGHQKGSDPSGDVRNEELAKLEIAVLAVIFVVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQLCWDITYRFRGPDWLCRVVKHLQVFAMFASAYMLVVMTADRYIAVCHPLKTLQQPTRRSRLMIAASWVLSFLLSTPQYFIFSMIEIEVNNGTKTQDCWATFIQPWGTRAYVTWMTSGVFVVPVVILGTCYGFICYHIWRNVRGKTASRQSKGSGEDVAPFHKGLLVTPCVSSVKTISRAKIRTVKMTFVIVTAYILCWAPFFIVQMWSVWDDNFIWTDSENPSITITALLASLNSCCNPWIYMFFSGHLLQDCVQSFPCCQRMVQKFTKDDSDNMSRRHTSYSNNRSPTNSTGTWKDSPKSSRSIRFIPVST
  
Inhibitor
Name:
BDBM50380760
Synonyms:
CHEMBL2017979
Type:
Small organic molecule
Emp. Form.:
C29H37N3O6S
Mol. Mass.:
555.686
SMILES:
COc1cc(OC2CCN(CC2)S(C)(=O)=O)ccc1CC(=O)N1CCC(CC1)N1C(=O)CCc2ccccc12
Structure:
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