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Target
Cannabinoid receptor 2
Ligand
BDBM50380892
Substrate
n/a
Meas. Tech.
ChEMBL_812810 (CHEMBL2020077)
IC50
24±n/a nM
Citation
 Odan, M; Ishizuka, N; Hiramatsu, Y; Inagaki, M; Hashizume, H; Fujii, Y; Mitsumori, S; Morioka, Y; Soga, M; Deguchi, M; Yasui, K; Arimura, A Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. Bioorg Med Chem Lett 22:2803-6 (2012) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50380892
Synonyms:
CHEMBL2019090 | S-777469
Type:
Small organic molecule
Emp. Form.:
C23H27FN2O4
Mol. Mass.:
414.4699
SMILES:
CCc1c(C)cc(C(=O)NC2(CCCCC2)C(O)=O)c(=O)n1Cc1ccc(F)cc1
Structure:
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