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Target
Neuropeptide Y receptor type 2
Ligand
BDBM50384239
Substrate
n/a
Meas. Tech.
ChEMBL_820067 (CHEMBL2032840)
IC50
483±n/a nM
Citation
 Mittapalli, GK; Vellucci, D; Yang, J; Toussaint, M; Brothers, SP; Wahlestedt, C; Roberts, E Synthesis and SAR of selective small molecule neuropeptide Y Y2 receptor antagonists. Bioorg Med Chem Lett 22:3916-20 (2012) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM50384239
Synonyms:
CHEMBL2030176
Type:
Small organic molecule
Emp. Form.:
C26H30N4O2S2
Mol. Mass.:
494.672
SMILES:
CN(C)S(=O)(=O)c1ccc(NC(=S)N2CCN(CC2)C(c2ccccc2)c2ccccc2)cc1
Structure:
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