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Target
Adenosine receptor A2b
Ligand
BDBM50350112
Substrate
n/a
Meas. Tech.
ChEMBL_824663 (CHEMBL2045828)
Ki
5820±n/a nM
Citation
 Gaspar, A; Reis, J; Matos, MJ; Uriarte, E; Borges, F In search for new chemical entities as adenosine receptor ligands: development of agents based on benzo-¿-pyrone skeleton. Eur J Med Chem 54:914-8 (2012) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50350112
Synonyms:
CHEMBL1814065
Type:
Small organic molecule
Emp. Form.:
C17H13NO5
Mol. Mass.:
311.2888
SMILES:
COc1ccc(NC(=O)c2coc3ccccc3c2=O)cc1O
Structure:
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