Reaction Details Report a problem with these data
Target
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Ligand
BDBM50388723
Substrate
n/a
Meas. Tech.
ChEMBL_829772 (CHEMBL2061291)
IC50
13440±n/a nM
Citation
 Mak, LH; Knott, J; Scott, KA; Scott, C; Whyte, GF; Ye, Y; Mann, DJ; Ces, O; Stivers, J; Woscholski, R Arylstibonic acids are potent and isoform-selective inhibitors of Cdc25a and Cdc25b phosphatases. Bioorg Med Chem 20:4371-6 (2012) [PubMed]  Article 
Target
Name:
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Synonyms:
MOSP | PLIP | PTEN-like phosphatase | PTPM1_HUMAN | PTPMT1 | Phosphoinositide lipid phosphatase | Protein-tyrosine phosphatase mitochondrial 1
Type:
PROTEIN
Mol. Mass.:
22857.40
Organism:
Homo sapiens (Human)
Description:
ChEMBL_829772
Residue:
201
Sequence:
MAATALLEAGLARVLFYPTLLYTLFRGKVPGRAHRDWYHRIDPTVLLGALPLRSLTRQLVQDENVRGVITMNEEYETRFLCNSSQEWKRLGVEQLRLSTVDMTGIPTLDNLQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPGQLDVLKEFHKQITARATKDGTFVISKT
  
Inhibitor
Name:
BDBM50388723
Synonyms:
CHEMBL2057662
Type:
Small organic molecule
Emp. Form.:
C9H11O5Sb
Mol. Mass.:
320.94
SMILES:
OC(=O)CCc1cccc(c1)[Sb](O)(O)=O
Structure:
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