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Target
Vesicular acetylcholine transporter
Ligand
BDBM50389433
Substrate
n/a
Meas. Tech.
ChEMBL_832039 (CHEMBL2065481)
Ki
9.3±n/a nM
Citation
 Kozaka, T; Uno, I; Kitamura, Y; Miwa, D; Ogawa, K; Shiba, K Syntheses and in vitro evaluation of decalinvesamicol analogues as potential imaging probes for vesicular acetylcholine transporter (VAChT). Bioorg Med Chem 20:4936-41 (2012) [PubMed]  Article 
Target
Name:
Vesicular acetylcholine transporter
Synonyms:
Slc18a3 | Solute carrier family 18 member 3 | VACHT_RAT | Vacht | Vat | rVAT
Type:
PROTEIN
Mol. Mass.:
56533.41
Organism:
Rattus norvegicus
Description:
ChEMBL_1503353
Residue:
530
Sequence:
MEPTAPTGQARAAATKLSEAVGAALQEPQRQRRLVLVIVCVALLLDNMLYMVIVPIVPDYIAHMRGGSEGPTLVSEVWEPTLPPPTLANASAYLANTSASPTAAGSARSILRPRYPTESEDVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVMFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAGKRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASEWEMGMVWLPAFVPHVLGVYLTVRLAARYPHLQWLYGALGLAVIGVSSCVVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRSERDVLLDEPPQGLYDAVRLREVQGKDGGEPCSPPGPFDGCEDDYNYYSRS
  
Inhibitor
Name:
BDBM50389433
Synonyms:
CHEMBL2064616
Type:
Small organic molecule
Emp. Form.:
C21H30BrNO
Mol. Mass.:
392.373
SMILES:
OC1C[C@@H]2CCCC[C@H]2CC1N1CCC(CC1)c1ccccc1Br |r|
Structure:
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