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Target
Vesicular acetylcholine transporter
Ligand
BDBM81982
Substrate
n/a
Meas. Tech.
ChEMBL_832039 (CHEMBL2065481)
Ki
1134±n/a nM
Citation
 Kozaka, T; Uno, I; Kitamura, Y; Miwa, D; Ogawa, K; Shiba, K Syntheses and in vitro evaluation of decalinvesamicol analogues as potential imaging probes for vesicular acetylcholine transporter (VAChT). Bioorg Med Chem 20:4936-41 (2012) [PubMed]  Article 
Target
Name:
Vesicular acetylcholine transporter
Synonyms:
Slc18a3 | Solute carrier family 18 member 3 | VACHT_RAT | Vacht | Vat | rVAT
Type:
PROTEIN
Mol. Mass.:
56533.41
Organism:
Rattus norvegicus
Description:
ChEMBL_1503353
Residue:
530
Sequence:
MEPTAPTGQARAAATKLSEAVGAALQEPQRQRRLVLVIVCVALLLDNMLYMVIVPIVPDYIAHMRGGSEGPTLVSEVWEPTLPPPTLANASAYLANTSASPTAAGSARSILRPRYPTESEDVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVMFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAGKRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASEWEMGMVWLPAFVPHVLGVYLTVRLAARYPHLQWLYGALGLAVIGVSSCVVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRSERDVLLDEPPQGLYDAVRLREVQGKDGGEPCSPPGPFDGCEDDYNYYSRS
  
Inhibitor
Name:
BDBM81982
Synonyms:
CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylguanidine | Tol2Gdn | cid_7333
Type:
Small organic molecule
Emp. Form.:
C15H17N3
Mol. Mass.:
239.3156
SMILES:
Cc1ccccc1NC(N)=Nc1ccccc1C |w:10.11|
Structure:
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