Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50389928
Substrate
n/a
Meas. Tech.
ChEMBL_834876 (CHEMBL2073236)
IC50
>10000±n/a nM
Citation
 Piscitelli, F; Ligresti, A; La Regina, G; Coluccia, A; Morera, L; Allarà, M; Novellino, E; Di Marzo, V; Silvestri, R Indole-2-carboxamides as allosteric modulators of the cannabinoid CB1 receptor. J Med Chem 55:5627-31 (2012) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50389928
Synonyms:
CHEMBL2071063
Type:
Small organic molecule
Emp. Form.:
C21H24ClN3O
Mol. Mass.:
369.888
SMILES:
CCc1c([nH]c2ccc(Cl)cc12)C(=O)NCCc1ccc(cc1)N(C)C
Structure:
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