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Target
Mu-type opioid receptor
Ligand
BDBM50391579
Substrate
n/a
Meas. Tech.
ChEMBL_850391 (CHEMBL2150811)
Ki
12.19±n/a nM
Citation
 Ida, Y; Matsubara, A; Nemoto, T; Saito, M; Hirayama, S; Fujii, H; Nagase, H Synthesis of quinolinomorphinan derivatives as highly selectived opioid receptor ligands. Bioorg Med Chem 20:5810-31 (2012) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44431.62
Organism:
MOUSE
Description:
OPIATE Mu OPRM1 MOUSE::P42866
Residue:
398
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50391579
Synonyms:
CHEMBL2147924
Type:
Small organic molecule
Emp. Form.:
C24H23N3O4
Mol. Mass.:
417.4571
SMILES:
CN1CC[C@]23Cc4nc5cccc([N+]([O-])=O)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:20:30.24.23|
Structure:
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