Reaction Details Report a problem with these data
Target
Hydroxycarboxylic acid receptor 1
Ligand
BDBM50391825
Substrate
n/a
Meas. Tech.
ChEMBL_850289 (CHEMBL2150709)
EC50
22000±n/a nM
Citation
 Dvorak, CA; Liu, C; Shelton, J; Kuei, C; Sutton, SW; Lovenberg, TW; Carruthers, NI Identification of Hydroxybenzoic Acids as Selective Lactate Receptor (GPR81) Agonists with Antilipolytic Effects. ACS Med Chem Lett 3:637-639 (2012) [PubMed]  Article 
Target
Name:
Hydroxycarboxylic acid receptor 1
Synonyms:
Gpr81 | HCAR1_MOUSE | Hcar1
Type:
PROTEIN
Mol. Mass.:
38945.31
Organism:
Mus musculus
Description:
ChEMBL_850289
Residue:
343
Sequence:
MDNGSCCLIEGEPISQVMPPLLILVFVLGALGNGIALCGFCFHMKTWKSSTIYLFNLAVADFLLMICLPLRTDYYLRRRHWIFGDIACRLVLFKLAMNRAGSIVFLTVVAVDRYFKVVHPHHMVNAISNRTAAATACVLWTLVILGTVYLLMESHLCVQGTLSSCESFIMESANGWHDVMFQLEFFLPLTIILFCSVNVVWSLRRRQQLTRQARMRRATRFIMVVASVFITCYLPSVLARLYFLWTVPTSACDPSVHTALHVTLSFTYLNSMLDPLVYYFSSPSLPKFYTKLTICSLKPKRPGRTKTRRSEEMPISNLCSKSSIDGANRSQRPSDGQWDLQVC
  
Inhibitor
Name:
BDBM50391825
Synonyms:
CHEMBL2146910
Type:
Small organic molecule
Emp. Form.:
C7H5ClO3
Mol. Mass.:
172.566
SMILES:
OC(=O)c1cc(O)cc(Cl)c1
Structure:
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