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Target
Cyclin-dependent kinase 1
Ligand
BDBM50321461
Substrate
n/a
Meas. Tech.
ChEMBL_862293 (CHEMBL2173149)
IC50
>20000±n/a nM
Citation
 Rotella, DP Recent results in protein kinase inhibition for tropical diseases. Bioorg Med Chem Lett 22:6788-93 (2012) [PubMed]  Article 
Target
Name:
Cyclin-dependent kinase 1
Synonyms:
CDC2 | CDC28A | CDK1 | CDK1_HUMAN | CDKN1 | Cell division control protein 2 homolog | Cell division protein kinase 1 | Cyclin-dependent kinase 1 (CDK1) | P34CDC2 | p34 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
34101.08
Organism:
Homo sapiens (Human)
Description:
P06493
Residue:
297
Sequence:
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
  
Inhibitor
Name:
BDBM50321461
Synonyms:
2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-phenylacetamide | CHEMBL1171238
Type:
Small organic molecule
Emp. Form.:
C12H8BrCl2NO3S2
Mol. Mass.:
429.137
SMILES:
Clc1cc(c(Cl)s1)S(=O)(=O)N(C(=O)CBr)c1ccccc1
Structure:
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