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Target
Cell division related protein kinase 2
Ligand
BDBM50397593
Substrate
n/a
Meas. Tech.
ChEMBL_862287 (CHEMBL2173143)
IC50
260±n/a nM
Citation
 Rotella, DP Recent results in protein kinase inhibition for tropical diseases. Bioorg Med Chem Lett 22:6788-93 (2012) [PubMed]  Article 
Target
Name:
Cell division related protein kinase 2
Synonyms:
CRK3 | Cdc2-related kinase | Cell division related protein kinase 2
Type:
PROTEIN
Mol. Mass.:
35647.04
Organism:
Leishmania major
Description:
ChEMBL_862288
Residue:
311
Sequence:
MSSFGRVTARSGDAGTRDSLDRYNRLDVLGEGTYGVVYRAVDKITGQYVALKKVRLDRTEEGIPQTALREVSILQEFDHPNIVNLLDVICSDGKLYLVFEYVEADLKKAIEKQEGGYSGMDLKRLIYQLLDGLYFCHRHRIIHRDLKPANILLTSGNVLKLADFGLARAFQVPMHTYTHEVVTLWYRAPEILLGEKHYTPAVDMWSVGCIFAELTRRKVLFRGDSEIGQLFEIFQVLGTPTDTEGSWPGVSRLPDYRDVFPKWTAKRLGQVLPELHPDAIDLLSKMLKYDPRERISAKEALQHPWFSDLRW
  
Inhibitor
Name:
BDBM50397593
Synonyms:
CHEMBL2171513
Type:
Small organic molecule
Emp. Form.:
C24H23N5O2
Mol. Mass.:
413.4717
SMILES:
CC(=O)c1cccc(c1)-c1cnn2ccc(Nc3ccc(cc3)N3CCOCC3)nc12
Structure:
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