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Target
Cell division related protein kinase 2
Ligand
BDBM78336
Substrate
n/a
Meas. Tech.
ChEMBL_862287 (CHEMBL2173143)
IC50
11000±n/a nM
Citation
 Rotella, DP Recent results in protein kinase inhibition for tropical diseases. Bioorg Med Chem Lett 22:6788-93 (2012) [PubMed]  Article 
Target
Name:
Cell division related protein kinase 2
Synonyms:
CRK3 | Cdc2-related kinase | Cell division related protein kinase 2
Type:
PROTEIN
Mol. Mass.:
35647.04
Organism:
Leishmania major
Description:
ChEMBL_862288
Residue:
311
Sequence:
MSSFGRVTARSGDAGTRDSLDRYNRLDVLGEGTYGVVYRAVDKITGQYVALKKVRLDRTEEGIPQTALREVSILQEFDHPNIVNLLDVICSDGKLYLVFEYVEADLKKAIEKQEGGYSGMDLKRLIYQLLDGLYFCHRHRIIHRDLKPANILLTSGNVLKLADFGLARAFQVPMHTYTHEVVTLWYRAPEILLGEKHYTPAVDMWSVGCIFAELTRRKVLFRGDSEIGQLFEIFQVLGTPTDTEGSWPGVSRLPDYRDVFPKWTAKRLGQVLPELHPDAIDLLSKMLKYDPRERISAKEALQHPWFSDLRW
  
Inhibitor
Name:
BDBM78336
Synonyms:
(6E)-6-[4-(3-pyridinylmethylamino)-1H-quinazolin-2-ylidene]-1-cyclohexa-2,4-dienone | (6E)-6-[4-(3-pyridylmethylamino)-1H-quinazolin-2-ylidene]cyclohexa-2,4-dien-1-one | (6E)-6-[4-(pyridin-3-ylmethylamino)-1H-quinazolin-2-ylidene]cyclohexa-2,4-dien-1-one | 2-{4-[(Pyridin-3-ylmethyl)-amino]-quinazolin-2-yl}-phenol | CHEMBL1328065 | MLS001043268 | SMR000415065 | cid_6097933
Type:
Small organic molecule
Emp. Form.:
C20H16N4O
Mol. Mass.:
328.3672
SMILES:
Oc1ccccc1-c1nc(NCc2cccnc2)c2ccccc2n1
Structure:
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