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Target
3-oxoacyl-[acyl-carrier-protein] synthase 1
Ligand
BDBM50401027
Substrate
n/a
Meas. Tech.
ChEMBL_881659 (CHEMBL2209290)
IC50
3800±n/a nM
Citation
 García, A; Bocanegra-García, V; Palma-Nicolás, JP; Rivera, G Recent advances in antitubercular natural products. Eur J Med Chem 49:1-23 (2012) [PubMed]  Article 
Target
Name:
3-oxoacyl-[acyl-carrier-protein] synthase 1
Synonyms:
β-ketoacyl-ACP synthase I (KasA) | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | Beta-ketoacyl-ACP synthase (KasA) | KASA_MYCTU | kasA
Type:
Protein
Mol. Mass.:
43305.57
Organism:
Mycobacterium tuberculosis
Description:
P9WQD9
Residue:
416
Sequence:
MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEFVTKWDLAVKIGGHLKDPVDSHMGRLDMRRMSYVQRMGKLLGGQLWESAGSPEVDPDRFAVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPNGAAAVIGLQLGARAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALMLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGLSPADIDHVNAHGTATPIGDAAEANAIRVAGCDQAAVYAPKSALGHSIGAVGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRYAVNNSFGFGGHNVALAFGRY
  
Inhibitor
Name:
BDBM50401027
Synonyms:
CHEMBL2204380
Type:
Small organic molecule
Emp. Form.:
C18H30O3
Mol. Mass.:
294.429
SMILES:
CCCCCCCc1cc(O)c(CCCCCC)c(=O)o1
Structure:
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