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Target
Carnitine O-palmitoyltransferase 1, muscle isoform
Ligand
BDBM50403030
Substrate
n/a
Meas. Tech.
ChEMBL_887375 (CHEMBL2216984)
IC50
>50000±n/a nM
Citation
 Ceccarelli, SM; Chomienne, O; Gubler, M; Arduini, A Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. J Med Chem 54:3109-52 (2011) [PubMed]  Article 
Target
Name:
Carnitine O-palmitoyltransferase 1, muscle isoform
Synonyms:
CPT I | CPT1-M | CPT1B | CPT1B_HUMAN | CPTI-M | Carnitine O-palmitoyltransferase I, muscle isoform | Carnitine palmitoyltransferase I-like protein | KIAA1670
Type:
PROTEIN
Mol. Mass.:
87823.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_887440
Residue:
772
Sequence:
MAEAHQAVAFQFTVTPDGVDFRLSREALKHVYLSGINSWKKRLIRIKNGILRGVYPGSPTSWLVVIMATVGSSFCNVDISLGLVSCIQRCLPQGCGPYQTPQTRALLSMAIFSTGVWVTGIFFFRQTLKLLLCYHGWMFEMHGKTSNLTRIWAMCIRLLSSRHPMLYSFQTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVLKSWWASNYVSDWWEEYIYLRGRSPLMVNSNYYVMDLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRIPGKDTDVLQHLSDSRHVAVYHKGRFFKLWLYEGARLLKPQDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQAFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPALAPPTRLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFLAEVLSEPWRLSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNAQRFGNHIRKALLDIADLFQVPKAYS
  
Inhibitor
Name:
BDBM50403030
Synonyms:
CHEMBL2216768
Type:
Small organic molecule
Emp. Form.:
C15H16ClF2O4
Mol. Mass.:
333.735
SMILES:
[O-]C(=O)C1(CO1)C(F)(F)CCCCCOc1ccc(Cl)cc1
Structure:
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