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Target
Carnitine O-palmitoyltransferase 1, muscle isoform
Ligand
BDBM80613
Substrate
n/a
Meas. Tech.
ChEMBL_887462 (CHEMBL2217071)
IC50
>100000±n/a nM
Citation
 Ceccarelli, SM; Chomienne, O; Gubler, M; Arduini, A Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. J Med Chem 54:3109-52 (2011) [PubMed]  Article 
Target
Name:
Carnitine O-palmitoyltransferase 1, muscle isoform
Synonyms:
CPT I | CPT1-M | CPT1B | CPT1B_HUMAN | CPTI-M | Carnitine O-palmitoyltransferase I, muscle isoform | Carnitine palmitoyltransferase I-like protein | KIAA1670
Type:
PROTEIN
Mol. Mass.:
87823.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_887440
Residue:
772
Sequence:
MAEAHQAVAFQFTVTPDGVDFRLSREALKHVYLSGINSWKKRLIRIKNGILRGVYPGSPTSWLVVIMATVGSSFCNVDISLGLVSCIQRCLPQGCGPYQTPQTRALLSMAIFSTGVWVTGIFFFRQTLKLLLCYHGWMFEMHGKTSNLTRIWAMCIRLLSSRHPMLYSFQTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVLKSWWASNYVSDWWEEYIYLRGRSPLMVNSNYYVMDLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRIPGKDTDVLQHLSDSRHVAVYHKGRFFKLWLYEGARLLKPQDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQAFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPALAPPTRLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFLAEVLSEPWRLSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNAQRFGNHIRKALLDIADLFQVPKAYS
  
Inhibitor
Name:
BDBM80613
Synonyms:
1-(2,3,4-Trimethoxy-benzyl)-piperazine | 1-(2,3,4-trimethoxybenzyl)piperazine;hydrochloride | 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine;hydrochloride | MLS001240268 | SMR000674573 | TRIMETAZIDINE | cid_9926449
Type:
Small organic molecule
Emp. Form.:
C14H22N2O3
Mol. Mass.:
266.3361
SMILES:
COc1ccc(CN2CCNCC2)c(OC)c1OC
Structure:
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