Reaction Details Report a problem with these data
Target
Beta-1 adrenergic receptor
Ligand
BDBM50404695
Substrate
n/a
Meas. Tech.
ChEMBL_39172 (CHEMBL654469)
Kd
2±n/a nM
Citation
 Lalloz, L; Loppinet, V; Coudert, G; Guillaumet, G; Loubinoux, B; Labrid, C; Beaughard, M; Dureng, G; Lamar, JC 2-Benzodioxinylaminoethanols: a new class of beta-adrenergic blocking and antihypertensive agents. J Med Chem 24:994-8 (1982) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1 | Adrenergic receptor | adrenergic Beta1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50540.48
Organism:
GUINEA PIG
Description:
adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73
Residue:
467
Sequence:
MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAGMGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVCTVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDEDEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
  
Inhibitor
Name:
BDBM50404695
Synonyms:
CHEMBL174853
Type:
Small organic molecule
Emp. Form.:
C20H23NO5
Mol. Mass.:
357.4003
SMILES:
COc1ccc(CCNCC(O)C2=COc3ccccc3O2)cc1OC |t:12|
Structure:
Search PDB for entries with ligand similarity: