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Target
Beta-2 adrenergic receptor
Ligand
BDBM50404695
Substrate
n/a
Meas. Tech.
ChEMBL_37850 (CHEMBL876540)
Kd
177.83±n/a nM
Citation
 Lalloz, L; Loppinet, V; Coudert, G; Guillaumet, G; Loubinoux, B; Labrid, C; Beaughard, M; Dureng, G; Lamar, JC 2-Benzodioxinylaminoethanols: a new class of beta-adrenergic blocking and antihypertensive agents. J Med Chem 24:994-8 (1982) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2_CAVPO | Adrb2 | adrenergic Beta2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46993.24
Organism:
GUINEA PIG
Description:
adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4
Residue:
418
Sequence:
MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNGKTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
  
Inhibitor
Name:
BDBM50404695
Synonyms:
CHEMBL174853
Type:
Small organic molecule
Emp. Form.:
C20H23NO5
Mol. Mass.:
357.4003
SMILES:
COc1ccc(CCNCC(O)C2=COc3ccccc3O2)cc1OC |t:12|
Structure:
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