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Target
Neuromedin-K receptor
Ligand
BDBM50406732
Substrate
n/a
Meas. Tech.
ChEMBL_141652 (CHEMBL749632)
Kd
3981.07±n/a nM
Citation
 Williams, BJ; Curtis, NR; McKnight, AT; Maguire, JJ; Young, SC; Veber, DF; Baker, R Cyclic peptides as selective tachykinin antagonists. J Med Chem 36:2-10 (1993) [PubMed]  Article 
Target
Name:
Neuromedin-K receptor
Synonyms:
NK3R_RAT | Neurokinin 3 receptor | Tac3r | Tacr3
Type:
n/a
Mol. Mass.:
51128.60
Organism:
Rattus norvegicus
Description:
ChEMBL_10983
Residue:
452
Sequence:
MASVPRGENWTDGTVEVGTHTGNLSSALGVTEWLALQAGNFSSALGLPATTQAPSQVRANLTNQFVQPSWRIALWSLAYGLVVAVAVFGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASVAAFNTLINFIYGLHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKIKVMPGRTLCYVQWPEGPKQHFTYHIIVIILVYCFPLLIMGVTYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVVTFAICWLPYHVYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIQVSSYDELELKTTRFHPTRQSSLYTVSRMESVTVLFDPNDGDPTKSSRKKRAVPRDPSANGCSHRGSKSASTTSSFISSPYTSVDEYS
  
Inhibitor
Name:
BDBM50406732
Synonyms:
CHEMBL269731
Type:
Small organic molecule
Emp. Form.:
C40H52N8O9S
Mol. Mass.:
820.954
SMILES:
CSCC[C@@H]1NC(=O)[C@@H](CC(C)C)N2C=CC(NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](CCC(N)=O)NC(=O)CNC1=O)C2=O |c:14|
Structure:
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