Reaction Details Report a problem with these data
Target
Translocator protein
Ligand
BDBM50408014
Substrate
n/a
Meas. Tech.
ChEMBL_38119 (CHEMBL650074)
IC50
500000000±n/a nM
Citation
 So, SS; Karplus, M Genetic neural networks for quantitative structure-activity relationships: improvements and application of benzodiazepine affinity for benzodiazepine/GABAA receptors. J Med Chem 39:5246-56 (1997) [PubMed]  Article 
Target
Name:
Translocator protein
Synonyms:
BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:
Enzyme
Mol. Mass.:
18834.74
Organism:
Homo sapiens (Human)
Description:
P30536
Residue:
169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
  
Inhibitor
Name:
BDBM50408014
Synonyms:
CHEMBL974 | N-Desalkyl-2-Oxoquazepam | Ro-05-3367
Type:
Small organic molecule
Emp. Form.:
C15H10ClFN2O
Mol. Mass.:
288.704
SMILES:
Fc1ccccc1C1=NCC(=O)Nc2ccc(Cl)cc12 |t:8|
Structure:
Search PDB for entries with ligand similarity: