Reaction Details Report a problem with these data
Target
Translocator protein
Ligand
BDBM50408023
Substrate
n/a
Meas. Tech.
ChEMBL_38119 (CHEMBL650074)
IC50
52600000±n/a nM
Citation
 So, SS; Karplus, M Genetic neural networks for quantitative structure-activity relationships: improvements and application of benzodiazepine affinity for benzodiazepine/GABAA receptors. J Med Chem 39:5246-56 (1997) [PubMed]  Article 
Target
Name:
Translocator protein
Synonyms:
BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:
Enzyme
Mol. Mass.:
18834.74
Organism:
Homo sapiens (Human)
Description:
P30536
Residue:
169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
  
Inhibitor
Name:
BDBM50408023
Synonyms:
CHEMBL346213 | Ro-20-8895
Type:
Small organic molecule
Emp. Form.:
C16H13FN2O
Mol. Mass.:
268.2856
SMILES:
Cc1ccc2c(NC(=O)CN=C2c2ccccc2F)c1 |c:10|
Structure:
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