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Target
RNA-directed RNA polymerase
Ligand
BDBM50410392
Substrate
n/a
Meas. Tech.
ChEMBL_302873 (CHEMBL828787)
Ki
327000±n/a nM
Citation
 Koh, YH; Shim, JH; Wu, JZ; Zhong, W; Hong, Z; Girardet, JL Design, synthesis, and antiviral activity of adenosine 5'-phosphonate analogues as chain terminators against hepatitis C virus. J Med Chem 48:2867-75 (2005) [PubMed]  Article 
Target
Name:
RNA-directed RNA polymerase
Synonyms:
Hepatitis C virus NS5B RNA-dependent RNA polymerase | NS5B protein
Type:
Protein
Mol. Mass.:
25173.95
Organism:
Hepatitis C virus
Description:
Q8JXU8
Residue:
229
Sequence:
RTEEAIYQCCDLDPQARVAIRSLTERLYVGGPLTNSRGENCGYRRRASGVLTTSCGNTLTCYIKAQAACRAAGRQDCTMLVCGDDLVVICESAGVQEDAASLRAFTEAMTRYSAPPGDPPQPEYDLELITSCSSNVSVAHDGAGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIMFAPTLWVRMIMLTHFFSVLIARDQLEQALDCEIYGACYSIEPLLPPIIQ
  
Inhibitor
Name:
BDBM50410392
Synonyms:
CHEMBL1161773
Type:
Small organic molecule
Emp. Form.:
C12H22N5O12P3
Mol. Mass.:
521.2507
SMILES:
C[C@@]1(O)[C@H](O)[C@@H](CCP(O)(=O)OP(O)(=O)OP(O)(O)O)O[C@H]1n1cnc2c(N)ncnc12 |r|
Structure:
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