Reaction Details Report a problem with these data
Target
Histidine-rich protein PFHRP-II
Ligand
BDBM50412201
Substrate
n/a
Meas. Tech.
ChEMBL_549674 (CHEMBL997303)
IC50
1720000000±n/a nM
Citation
 Van Miert, S; Hostyn, S; Maes, BU; Cimanga, K; Brun, R; Kaiser, M; Mátyus, P; Dommisse, R; Lemière, G; Vlietinck, A; Pieters, L Isoneocryptolepine, a synthetic indoloquinoline alkaloid, as an antiplasmodial lead compound. J Nat Prod 68:674-7 (2005) [PubMed]  Article 
Target
Name:
Histidine-rich protein PFHRP-II
Synonyms:
HRP1_PLAFA | Histidine-rich protein | Histidine-rich protein PFHRP-II
Type:
PROTEIN
Mol. Mass.:
35156.49
Organism:
Plasmodium falciparum
Description:
ChEMBL_500704
Residue:
332
Sequence:
MVSFSKNKVLSAAVFASVLLLDNNNSAFNNNLCSKNAKGLNLNKRLLHETQAHVDDAHHAHHVADAHHAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAAYAHHAHHASDAHHAADAHHAAYAHHAHHAADAHHAADAHHAAYAHHAHHAADAHHAADAHHATDAHHAHHAADAHHATDAHHAADAHHAADAHHATDAHHAADAHHATDAHHAADAHHAADAHHATDSHHAHHAADAHHAAAHHATDAHHAAAHHATDAHHAAAHHEAATHCLRH
  
Inhibitor
Name:
BDBM50412201
Synonyms:
CRYPTOLEPINE HYDROCHLORIDE | Cryptolepine
Type:
Small organic molecule
Emp. Form.:
C16H12N2
Mol. Mass.:
232.2799
SMILES:
Cn1c2c(cc3ccccc13)nc1ccccc21
Structure:
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