Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50415880
Substrate
n/a
Meas. Tech.
ChEMBL_629911 (CHEMBL1108375)
Ki
15.85±n/a nM
Citation
 Areias, FM; Brea, J; Gregori-Puigjané, E; Zaki, ME; Carvalho, MA; Domínguez, E; Gutiérrez-de-Terán, H; Proença, MF; Loza, MI; Mestres, J In silico directed chemical probing of the adenosine receptor family. Bioorg Med Chem 18:3043-52 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50415880
Synonyms:
CHEMBL1097489
Type:
Small organic molecule
Emp. Form.:
C21H19N3O3
Mol. Mass.:
361.3939
SMILES:
CCn1n2c(nc(O)c2c2ccccc2c1=O)-c1cccc(OCC=C)c1
Structure:
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