Reaction Details Report a problem with these data
Target
Somatostatin receptor type 2
Ligand
BDBM50423349
Substrate
n/a
Meas. Tech.
ChEMBL_456105 (CHEMBL888114)
Kd
8710±n/a nM
Citation
 Hurth, K; Enz, A; Floersheim, P; Gentsch, C; Hoyer, D; Langenegger, D; Neumann, P; Pfäffli, P; Sorg, D; Swoboda, R; Vassout, A; Troxler, T SAR of the arylpiperazine moiety of obeline somatostatin sst1 receptor antagonists. Bioorg Med Chem Lett 17:3988-91 (2007) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SRIF-1 | SS2R | SSR2_RAT | Somatostatin receptor | Somatostatin receptor 2 | Somatostatin receptor type 2 | Sstr2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41212.21
Organism:
RAT
Description:
SOMATOSTATIN SST2 SSTR2 RAT::P30680
Residue:
369
Sequence:
MELTSEQFNGSQVWIPSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGAEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM50423349
Synonyms:
CHEMBL250705
Type:
Small organic molecule
Emp. Form.:
C28H35N3O3
Mol. Mass.:
461.5958
SMILES:
COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cc3)C(C)=O)Cc12
Structure:
Search PDB for entries with ligand similarity: