Reaction Details Report a problem with these data
Target
Ricin
Ligand
BDBM50424232
Substrate
n/a
Meas. Tech.
ChEMBL_934991 (CHEMBL2320360)
IC50
35000±n/a nM
Citation
 Saito, R; Pruet, JM; Manzano, LA; Jasheway, K; Monzingo, AF; Wiget, PA; Kamat, I; Anslyn, EV; Robertus, JD Peptide-conjugated pterins as inhibitors of ricin toxin A. J Med Chem 56:320-9 (2013) [PubMed]  Article 
Target
Name:
Ricin
Synonyms:
RICI_RICCO
Type:
PROTEIN
Mol. Mass.:
64090.82
Organism:
Ricinus communis
Description:
ChEMBL_1286970
Residue:
576
Sequence:
MKPGGNTIVIWMYAVATWLCFGSTSGWSFTLEDNNIFPKQYPIINFTTAGATVQSYTNFIRAVRGRLTTGADVRHEIPVLPNRVGLPINQRFILVELSNHAELSVTLALDVTNAYVVGYRAGNSAYFFHPDNQEDAEAITHLFTDVQNRYTFAFGGNYDRLEQLAGNLRENIELGNGPLEEAISALYYYSTGGTQLPTLARSFIICIQMISEAARFQYIEGEMRTRIRYNRRSAPDPSVITLENSWGRLSTAIQESNQGAFASPIQLQRRNGSKFSVYDVSILIPIIALMVYRCAPPPSSQFSLLIRPVVPNFNADVCMDPEPIVRIVGRNGLCVDVRDGRFHNGNAIQLWPCKSNTDANQLWTLKRDNTIRSNGKCLTTYGYSPGVYVMIYDCNTAATDATRWQIWDNGTIINPRSSLVLAATSGNSGTTLTVQTNIYAVSQGWLPTNNTQPFVTTIVGLYGLCLQANSGQVWIEDCSSEKAEQQWALYADGSIRPQQNRDNCLTSDSNIRETVVKILSCGPASSGQRWMFKNDGTILNLYSGLVLDVRASDPSLKQIILYPLHGDPNQIWLPLF
  
Inhibitor
Name:
BDBM50424232
Synonyms:
CHEMBL2314133
Type:
Small organic molecule
Emp. Form.:
C24H28N8O6
Mol. Mass.:
524.5291
SMILES:
CC(C)C[C@H](NC(=O)CNC(=O)c1cnc2c(nc(N)[nH]c2=O)n1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r|
Structure:
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