Reaction Details Report a problem with these data
Target
Galectin-3
Ligand
BDBM50425517
Substrate
n/a
Meas. Tech.
ChEMBL_936059 (CHEMBL2319301)
Kd
1200±n/a nM
Citation
 van Hattum, H; Branderhorst, HM; Moret, EE; Nilsson, UJ; Leffler, H; Pieters, RJ Tuning the preference of thiodigalactoside- and lactosamine-based ligands to galectin-3 over galectin-1. J Med Chem 56:1350-4 (2013) [PubMed]  Article 
Target
Name:
Galectin-3
Synonyms:
LEG3_HUMAN | LGALS3 | MAC2
Type:
Enzyme
Mol. Mass.:
26156.54
Organism:
Homo sapiens (Human)
Description:
P17931
Residue:
250
Sequence:
MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
  
Inhibitor
Name:
BDBM50425517
Synonyms:
CHEMBL2313337
Type:
Small organic molecule
Emp. Form.:
C36H40N4O13
Mol. Mass.:
736.7218
SMILES:
OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@@H](OCCCN=[N+]=[N-])[C@@H]([C@H]2O)N2C(=O)c3ccccc3C2=O)[C@H](O)[C@@H](OCc2ccc(Oc3ccccc3)cc2)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: