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Target
P2Y purinoceptor 14
Ligand
BDBM50429535
Substrate
n/a
Meas. Tech.
ChEMBL_945218 (CHEMBL2339544)
Ki
>15000±n/a nM
Citation
 Chao, H; Turdi, H; Herpin, TF; Roberge, JY; Liu, Y; Schnur, DM; Poss, MA; Rehfuss, R; Hua, J; Wu, Q; Price, LA; Abell, LM; Schumacher, WA; Bostwick, JS; Steinbacher, TE; Stewart, AB; Ogletree, ML; Huang, CS; Chang, M; Cacace, AM; Arcuri, MJ; Celani, D; Wexler, RR; Lawrence, RM Discovery of 2-(phenoxypyridine)-3-phenylureas as small molecule P2Y1 antagonists. J Med Chem 56:1704-14 (2013) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 14
Synonyms:
GPR105 | Insulin Receptor-Related Protein (INSRR) | KIAA0001 | P2RY14 | P2Y14_HUMAN | Purinergic receptor P2Y14
Type:
PROTEIN
Mol. Mass.:
38991.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1502487
Residue:
338
Sequence:
MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
  
Inhibitor
Name:
BDBM50429535
Synonyms:
CHEMBL2333772
Type:
Small organic molecule
Emp. Form.:
C25H29N3O2
Mol. Mass.:
403.5167
SMILES:
CC(C)c1ccccc1Oc1ncccc1NC(=O)Nc1ccc(cc1)C(C)(C)C
Structure:
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