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Target
Cyclin-dependent kinase 2
Ligand
BDBM50432365
Substrate
n/a
Meas. Tech.
ChEMBL_951877 (CHEMBL2353290)
IC50
2700±n/a nM
Citation
 Bryan, MC; Falsey, JR; Frohn, M; Reichelt, A; Yao, G; Bartberger, MD; Bailis, JM; Zalameda, L; Miguel, TS; Doherty, EM; Allen, JG N-substituted azaindoles as potent inhibitors of Cdc7 kinase. Bioorg Med Chem Lett 23:2056-60 (2013) [PubMed]  Article 
Target
Name:
Cyclin-dependent kinase 2
Synonyms:
CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
33938.17
Organism:
Homo sapiens (Human)
Description:
P24941
Residue:
298
Sequence:
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
  
Inhibitor
Name:
BDBM50432365
Synonyms:
CHEMBL2348182
Type:
Small organic molecule
Emp. Form.:
C14H11N5
Mol. Mass.:
249.2706
SMILES:
CNc1nccc(n1)-n1ccc2ccc(cc12)C#N
Structure:
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