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Target
Leukotriene C4 synthase
Ligand
BDBM50434668
Substrate
n/a
Meas. Tech.
ChEMBL_961179 (CHEMBL2389915)
IC50
>3000±n/a nM
Citation
 Shiro, T; Kakiguchi, K; Takahashi, H; Nagata, H; Tobe, M 7-Phenyl-imidazoquinolin-4(5H)-one derivatives as selective and orally available mPGES-1 inhibitors. Bioorg Med Chem 21:2868-78 (2013) [PubMed]  Article 
Target
Name:
Leukotriene C4 synthase
Synonyms:
LTC4 synthase | LTC4S | LTC4S_HUMAN | Leukotriene-C(4) synthase
Type:
PROTEIN
Mol. Mass.:
16575.59
Organism:
Homo sapiens (Human)
Description:
ChEMBL_961179
Residue:
150
Sequence:
MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAALGLLAHFLPAALRAALLGRLRTLLPWA
  
Inhibitor
Name:
BDBM50434668
Synonyms:
CHEMBL2387503
Type:
Small organic molecule
Emp. Form.:
C22H13ClFN3O
Mol. Mass.:
389.81
SMILES:
Fc1cccc(Cl)c1-c1nc2c([nH]1)c(=O)[nH]c1cc(ccc21)-c1ccccc1
Structure:
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