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Target
Translocator protein
Ligand
BDBM50442394
Substrate
n/a
Meas. Tech.
ChEMBL_991140 (CHEMBL2446596)
Ki
8.0±n/a nM
Citation
 Fukaya, T; Ishiyama, T; Baba, S; Masumoto, S Identification of a novel benzoxazolone derivative as a selective, orally active 18 kDa translocator protein (TSPO) ligand. J Med Chem 56:8191-5 (2013) [PubMed]  Article 
Target
Name:
Translocator protein
Synonyms:
BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:
Enzyme
Mol. Mass.:
18834.74
Organism:
Homo sapiens (Human)
Description:
P30536
Residue:
169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
  
Inhibitor
Name:
BDBM50442394
Synonyms:
CHEMBL2442940
Type:
Small organic molecule
Emp. Form.:
C22H16F3N3O3
Mol. Mass.:
427.3759
SMILES:
CN(C(=O)Cn1c2cc(ccc2oc1=O)-c1cccnc1)c1ccc(cc1)C(F)(F)F
Structure:
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