Reaction Details Report a problem with these data
Target
Proline racemase
Ligand
BDBM50444845
Substrate
n/a
Meas. Tech.
ChEMBL_1282556 (CHEMBL3101223)
Ki
5800±n/a nM
Citation
 Harty, M; Nagar, M; Atkinson, L; Legay, CM; Derksen, DJ; Bearne, SL Inhibition of serine and proline racemases by substrate-product analogues. Bioorg Med Chem Lett 24:390-3 (2013) [PubMed]  Article 
Target
Name:
Proline racemase
Synonyms:
prdF
Type:
PROTEIN
Mol. Mass.:
32973.46
Organism:
Clostridium sticklandii
Description:
ChEMBL_107984
Residue:
299
Sequence:
MADKKKYLEDNLDYVRTALMHEPRGHNDMFGSIITSSNNKEADFGIIFMDGGGYLNMCGHGSIGAATVAVETGMVEMVEPVTNINMEAPAGLIKAKVMVENEKVKEVSITNVPSFLYMEDAKLEVPSLNKTITFDISFGGSFFAIIHAKELGVKVETSQVDVLKKLGIEIRDLINEKIKVQHPELEHIKTVDLVEIYDEPSNPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLYKKGHLKIDEKFVYESITGTMFKGRVLEETKVGEFDAIIPEITGGAYITGFNHFVIDPLKYGFTV
  
Inhibitor
Name:
BDBM50444845
Synonyms:
CHEMBL1235532
Type:
Small organic molecule
Emp. Form.:
C5H4NO2
Mol. Mass.:
110.0913
SMILES:
[O-]C(=O)c1ccc[nH]1
Structure:
Search PDB for entries with ligand similarity: