Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50453368
Substrate
n/a
Meas. Tech.
ChEMBL_201908 (CHEMBL873466)
IC50
1800±n/a nM
Citation
 Seri-Levy, A; West, S; Richards, WG Molecular similarity, quantitative chirality, and QSAR for chiral drugs. J Med Chem 37:1727-32 (1994) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50453368
Synonyms:
CHEMBL47900
Type:
Small organic molecule
Emp. Form.:
C19H23NO
Mol. Mass.:
281.392
SMILES:
CCc1ccc(cc1)N1CCC[C@H](C1)c1cccc(O)c1
Structure:
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