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Target
Ornithine decarboxylase
Ligand
BDBM50009924
Substrate
n/a
Meas. Tech.
ChEMBL_1344637 (CHEMBL3254299)
Ki
70000±n/a nM
Citation
 Bey, P; Danzin, C; Van Dorsselaer, V; Mamont, P; Jung, M; Tardif, C Analogues of ornithine as inhibitors of ornithine decarboxylase. New deductions concerning the topography of the enzyme's active site. J Med Chem 21:50-5 (1978) [PubMed]  Article 
Target
Name:
Ornithine decarboxylase
Synonyms:
DCOR_RAT | Odc | Odc1
Type:
PROTEIN
Mol. Mass.:
51037.04
Organism:
Rattus norvegicus
Description:
ChEMBL_1344641
Residue:
461
Sequence:
MGSFTKEEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDVLKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPPERIIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMGTEVGFSMYLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQTGSDDEDESNEQTLMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCSLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRSMWQLMKQIQSHGFPPEVEEQDVGTLPMSCAQESGMDRHPAACASASINV
  
Inhibitor
Name:
BDBM50009924
Synonyms:
CHEMBL3247542
Type:
Small organic molecule
Emp. Form.:
C7H14N2O2
Mol. Mass.:
158.1983
SMILES:
N[C@H]1CC[C@@](N)(CC1)C(O)=O |r,wU:4.8,wD:1.0,(19.99,-29.56,;19.99,-28.02,;21.32,-27.25,;21.32,-25.71,;19.99,-24.94,;20.74,-23.6,;18.66,-25.71,;18.66,-27.25,;19.19,-23.6,;17.65,-23.63,;19.93,-22.26,)|
Structure:
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