Reaction Details Report a problem with these data
Target
Glandular kallikrein
Ligand
BDBM50009971
Substrate
n/a
Meas. Tech.
ChEMBL_1342913 (CHEMBL3259188)
Ki
18900±n/a nM
Citation
 Tidwell, RR; Geratz, JD; Dann, O; Volz, G; Zeh, D; Loewe, H Diarylamidine derivatives with one or both of the aryl moieties consisting of an indole or indole-like ring. Inhibitors of arginine-specific esteroproteases. J Med Chem 21:613-23 (1978) [PubMed]  Article 
Target
Name:
Glandular kallikrein
Synonyms:
KLK_PIG | Tissue kallikrein
Type:
PROTEIN
Mol. Mass.:
26710.38
Organism:
Sus scrofa
Description:
ChEMBL_108296
Residue:
242
Sequence:
APPIQSRIIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNLFENENTAQFFGVTADFPHPGFNLSLLKHTKADGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPELGSTCEASGWGSIEPGPDFEFPDEIQCVQLTLLQNTFCAAHPKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWGHTPCGSANKPSIYTKLIFYLDWINDTITENP
  
Inhibitor
Name:
BDBM50009971
Synonyms:
CHEMBL3251186
Type:
Small organic molecule
Emp. Form.:
C17H17N5
Mol. Mass.:
291.3504
SMILES:
Cn1c(cc2ccc(cc12)C(N)=N)-c1ccc(cc1)C(N)=N
Structure:
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