Reaction Details Report a problem with these data
Target
Pyridoxal kinase
Ligand
BDBM50016820
Substrate
n/a
Meas. Tech.
ChEMBL_1360674 (CHEMBL3282832)
Ki
125000±n/a nM
Citation
 Korytnyk, W; Potti, PG 4-Halovinyl- and 4-ethynyl-4-deformylpyridoxal derivatives and related analogues as potentially irreversible antagonists of vitamin B6. J Med Chem 20:567-72 (1977) [PubMed]  Article 
Target
Name:
Pyridoxal kinase
Synonyms:
C21orf124 | C21orf97 | PDXK | PDXK_HUMAN | PKH | PNK | Pyridoxine kinase
Type:
PROTEIN
Mol. Mass.:
35099.40
Organism:
Homo sapiens (Human)
Description:
ChEMBL_103125
Residue:
312
Sequence:
MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDIEDPEIVVQATVL
  
Inhibitor
Name:
BDBM50016820
Synonyms:
CHEMBL3275146
Type:
Small organic molecule
Emp. Form.:
C9H9NO2
Mol. Mass.:
163.1733
SMILES:
Cc1ncc(CO)c(C#C)c1O
Structure:
Search PDB for entries with ligand similarity: