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Target
Retinol-binding protein 4
Ligand
BDBM50019035
Substrate
n/a
Meas. Tech.
ChEMBL_1361118 (CHEMBL3291833)
IC50
>30000±n/a nM
Citation
 Wang, Y; Connors, R; Fan, P; Wang, X; Wang, Z; Liu, J; Kayser, F; Medina, JC; Johnstone, S; Xu, H; Thibault, S; Walker, N; Conn, M; Zhang, Y; Liu, Q; Grillo, MP; Motani, A; Coward, P; Wang, Z Structure-assisted discovery of the first non-retinoid ligands for Retinol-Binding Protein 4. Bioorg Med Chem Lett 24:2885-91 (2014) [PubMed]  Article 
Target
Name:
Retinol-binding protein 4
Synonyms:
PRBP | Plasma retinol-binding protein | RBP | RBP4 | RET4_HUMAN | Retinol-binding protein 4 | Retinol-binding protein 4 (RBP4) | spa binding assay for rbp4
Type:
Protein
Mol. Mass.:
23008.75
Organism:
Homo sapiens (Human)
Description:
P02753
Residue:
201
Sequence:
MKWVWALLLLAALGSGRAERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYCDGRSERNLL
  
Inhibitor
Name:
BDBM50019035
Synonyms:
CHEMBL3288139
Type:
Small organic molecule
Emp. Form.:
C17H19ClN4O2
Mol. Mass.:
346.811
SMILES:
COc1ccc(Cl)cc1NC(=O)N1CCN(CC1)c1ccccn1
Structure:
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