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Target
Cathepsin B
Ligand
BDBM50338854
Substrate
n/a
Meas. Tech.
ChEMBL_1459865 (CHEMBL3367288)
Ki
40000±n/a nM
Citation
 Raghav, N; Singh, M SAR studies of differently functionalized chalcones based hydrazones and their cyclized derivatives as inhibitors of mammalian cathepsin B and cathepsin H. Bioorg Med Chem 22:4233-45 (2014) [PubMed]  Article 
Target
Name:
Cathepsin B
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
36777.57
Organism:
Capra hircus (Goat)
Description:
n/a
Residue:
335
Sequence:
MWQLLATLSCLLVLTSARSSLHFPPLSDEMVNYVNKQNTTWKAGHNFYNVDLSYVKKLCGAILGGPKLPQRDAFAADMVLPDSFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSKGRVNVEVSAEDMLTCCGSECGDGCNGGFPSGAWNFWTKKGLVSGGLYDSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPSYKDDKHFGCSSYSVSSNEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEMMGGHAIRILGWGVENDTPYWLVGNSWNTDWGDKGFFKILRGQDHCGIESEIVAGMPCTHQY
  
Inhibitor
Name:
BDBM50338854
Synonyms:
3,5-diphenyl-4,5-dihydro-1H-pyrazole | CHEMBL1684781
Type:
Small organic molecule
Emp. Form.:
C15H14N2
Mol. Mass.:
222.2851
SMILES:
C1C(N=NC1c1ccccc1)c1ccccc1 |c:2|
Structure:
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