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Target
Galectin-3
Ligand
BDBM50048092
Substrate
n/a
Meas. Tech.
ChEMBL_1454623 (CHEMBL3361812)
Kd
130000±n/a nM
Citation
 Rajput, VK; Leffler, H; Nilsson, UJ; Mukhopadhyay, B Synthesis and evaluation of iminocoumaryl and coumaryl derivatized glycosides as galectin antagonists. Bioorg Med Chem Lett 24:3516-20 (2014) [PubMed]  Article 
Target
Name:
Galectin-3
Synonyms:
LEG3_HUMAN | LGALS3 | MAC2
Type:
Enzyme
Mol. Mass.:
26156.54
Organism:
Homo sapiens (Human)
Description:
P17931
Residue:
250
Sequence:
MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
  
Inhibitor
Name:
BDBM50048092
Synonyms:
CHEMBL3311521
Type:
Small organic molecule
Emp. Form.:
C29H35NO14S
Mol. Mass.:
653.652
SMILES:
[H][C@@]1(O[C@@H]2[C@@H](CO)O[C@@H](OCc3cc4ccccc4o\c3=N/S(=O)(=O)c3ccc(C)cc3)[C@H](O)[C@H]2O)O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O |r|
Structure:
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