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Target
Carbonic anhydrase 2
Ligand
BDBM50058823
Substrate
n/a
Meas. Tech.
ChEMBL_1452411 (CHEMBL3362073)
Ki
1110±n/a nM
Citation
 Schwarz, S; Sommerwerk, S; Lucas, SD; Heller, L; Csuk, R Sulfamates of methyl triterpenoates are effective and competitive inhibitors of carbonic anhydrase II. Eur J Med Chem 86:95-102 (2014) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA2 | CAH2_BOVIN | Carbonic anhydrase | Carbonic anhydrase 2 | Carbonic anhydrase II | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29115.93
Organism:
Bos taurus
Description:
n/a
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIANGERQSPVDIDTKAVVQDPALKPLALVYGEATSRRMVNNGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAELHLVHWNTKYGDFGTAAQQPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPNFDPGSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPELLMLANWRPAQPLKNRQVRGFPK
  
Inhibitor
Name:
BDBM50058823
Synonyms:
CHEMBL3325726
Type:
Small organic molecule
Emp. Form.:
C31H51NO5S
Mol. Mass.:
549.805
SMILES:
[H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@]5(CC[C@@]34C)C(=O)OC)[C@@]1(C)CC[C@H](OS(N)(=O)=O)C2(C)C |r,t:9|
Structure:
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