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Target
5-hydroxytryptamine receptor 6
Ligand
BDBM50068241
Substrate
n/a
Meas. Tech.
ChEMBL_1464328 (CHEMBL3404595)
Ki
3104±n/a nM
Citation
 Smusz, S; Kurczab, R; Satala, G; Bojarski, AJ Fingerprint-based consensus virtual screening towards structurally new 5-HT(6)R ligands. Bioorg Med Chem Lett 25:1827-30 (2015) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 6
Synonyms:
5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
46968.43
Organism:
Homo sapiens (Human)
Description:
P50406
Residue:
440
Sequence:
MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN
  
Inhibitor
Name:
BDBM50068241
Synonyms:
CHEMBL3403335
Type:
Small organic molecule
Emp. Form.:
C23H18N2O2S
Mol. Mass.:
386.466
SMILES:
O=S(=O)(N1C=Cc2ccccc2C1c1c[nH]c2ccccc12)c1ccccc1 |c:4|
Structure:
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